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Whether or not this can even be accomplished is uncertain at this time and represents one of the forefronts of research into GHI vaccines.What IS known is that the many Herpes vaccines that have been produced, almost without exception, generate very strong immune responses in the animals and humans to which they are given.
Herpes virus infects the nerve cells, getting into the cells directly inside the skin and then traveling up the dendrites and nerves to the nerve cells by the spinal cord.That alone would decrease the transmission rate, as it should.A vaccine uses a product of the body’s immune system to kill virus particles, either antibody (liquid protein floating around in the blood and body fluid) which is directly targeted toward proteins on the virus, OR lymphocytes (white blood cells that are turned on by the immune system to fight infection) that are targeted toward some of the same proteins on the virus.Both vaccines are available for those interested, but one might have to travel to that country to take it.The Bottom Line: There MAY be some benefit from these vaccines to reducing recurrence frequency.They do NOT eradicate the virus from the body, however, and do not prevent recurrences.
Numerous articles have suggested that these European vaccines also reduce transmission of GHI to non-infected partners. Read this carefully, though, before you consider booking a flight: It is difficult to separate out from the effect of the vaccine the other effect of “patient counseling”, that is, being “smart” about managing GHI.
Further reading will add greater depth to your reference information, but you need only read a few paragraphs to get the gist.
Vaccines for GHI have been being produced for at least twenty years, especially in Europe.
For example, the injected DNA might cause the body to produce the “G antigen” of Herpes Simplex Type 2. A scientific paper published in early 1999 studying Herpes infections in mice found that a new DNA vaccine causing production of a certain herpes virus protein modified with bupivicaine in fact caused perhaps a 99% reduction in the ability to infect mice with “Herpes challenges” in the vaginas of the mice.
This antigen (which is only a tiny, tiny portion of the virus membrane and does NOT cause any sort of infection) stimulates an intense production of antibody against the “G antigen” of HSV2. The DNA vaccine efforts for GHI are only just now being explored and are probably 3 or 4 years away from substantial information being generated. This is, perhaps, the most encouraging evidence to date that in the not too distant future, a vaccine will be produced against genital herpes infections that will at least dramatically reduce the transmission of Herpes, if not virtually eliminate it.
The results of almost all of this information, when looking at the literature honestly, is that the vaccines may offer a very slight benefit for preventing transmission and treating infection. Specifically, Mastrolorenzo’s previous work in Florence used multiple injections of vaccine over many weeks to produce a modest reduction in outbreak frequency among infected women. Vaccine developed in England gave initially high marks for reducing recurrences and preventing transmission.